CANINE PANCREATIC LIPASE (cPL)

Description

Canine Pancreatic Lipase (cPL) Test – Diagnosis of Pancreatitis in Dogs

The Canine Pancreatic Lipase (cPL) Test is a species-specific, highly sensitive immunoassay that measures the concentration of pancreas-specific lipase in a dog’s serum. It is the gold-standard blood test for diagnosing pancreatitis in dogs and is significantly more sensitive than conventional serum amylase or lipase tests.

At Home Petcare, powered by Diagnopet, offers at-home blood sample collection for the Canine Pancreatic Lipase test across Hyderabad, making this critical diagnostic available at your doorstep.

What Is Pancreatitis in Dogs?

Pancreatitis is inflammation of the pancreas — a vital organ responsible for digestive enzyme production and insulin secretion. It is one of the most common gastrointestinal conditions in dogs and can range from mild and self-limiting to severe, life-threatening disease. The pancreas-specific lipase enzyme leaks into the bloodstream when pancreatic acinar cells are damaged, making cPL a direct and sensitive marker of pancreatic injury.

Why cPL Over Conventional Lipase Tests?

• Organ Specificity: Unlike conventional serum lipase assays, cPL exclusively measures lipase of pancreatic origin — eliminating false positives from extra-pancreatic sources (liver, intestine, kidneys).
• Higher Sensitivity: The Spec cPL assay has 71% sensitivity for moderate-to-severe pancreatitis and is more reliable than serum amylase or conventional lipase.
• Treatment Monitoring: cPL levels can be monitored serially to assess response to treatment and guide clinical decisions.
• Early Diagnosis: cPL is cleared from the blood rapidly, making it a dynamic and responsive marker ideal for monitoring clinical progression.

When Is This Test Recommended?

• Dogs with vomiting, abdominal pain, lethargy, or loss of appetite
• Dogs with elevated serum amylase or lipase on routine biochemistry
• Dogs on high-fat diets, obese dogs, or breeds predisposed to pancreatitis (Miniature Schnauzers, Cocker Spaniels, Yorkshire Terriers)
• Dogs with diabetes mellitus or other metabolic diseases where pancreatitis may be a co-morbidity
• Post-surgical monitoring in dogs at risk for pancreatic complications
• Monitoring dogs during treatment for acute pancreatitis

Reference Ranges

• Normal: < 200 ng/mL (Spec cPL)
• Equivocal: 200–400 ng/mL — repeat testing recommended
• Elevated (Pancreatitis likely): > 400 ng/mL

Sample Type

Serum (Blood) – Collected at your home in Hyderabad by our trained veterinary professionals. Fasting the dog for at least 4–6 hours before collection is recommended.

Report Delivery

Digital report delivered within 24–48 hours via email and WhatsApp.